Services

  • BIOLOGICAL E. LTD.
    Vaccine Production
  • WOCKHARDT LTD.
    Insulin Production Facility
  • SANZYME LTD.
    Fermentation Facility
  • KASIAK RESEARCH
    Human & Animal Tissue Culture Laboratory
  • TEX-BIOSCIENCE PVT. LTD.
    Animal Feed Manufacturing Facility

Client Name
Biologocal E. Ltd.

Facility Type
Vaccine Production

Project Location
Hyderabad, India

Project Duration
14 months

Services Provided
  • Project Management
  • Basic Engineering
  • Detailed Engineering
  • Procurement Assistance
  • Validation Support
Key Project Features
Biological E. was established over 50 years ago. It is the first private sector biological products company in India and the first pharmaceuticals company in South India. BE is also the pioneer in preventive medicine.

The facility was designed as multi-purpose facility to facilitate manufacturing of bulk vaccines on campaign basis. The facility will be designed for 100 million doses/ year of each bulk vaccine under cGMP conditions. Required unit operations such as cell propagation, incubation, Virus infection, virus incubation, harvesting, Media preparation and storage.

The facility was designed in accordance of containment requirement for managing infectious agents of BSL 2 category. The design objective is to protect the operators and others from exposure and also to protect the outside environment from potentially hazardous / infectious agents.

Client Name
Wockhardt Ltd.

Facility Type
Insulin Production Facility

Project Location
Aurangabad, India

Project Duration
7 months

Services Provided
  • Review of Conceptual Design
  • Basic Engineering
  • Detail Engineering
  • Procurement Assistance
  • Validation Support
Key Project Features
Wockhardt Ltd is one of the leading Pharmaceutical and Biotech manufacturer in India and also has manufacturing facilities in US and UK. This facility was the expansion of their existing facility named as “Plant D, Phase-I”.

The proposed facility was planned, designed and engineered as per cGMP standards and shall confirm to all relevant local statuary/regulatory and cGMP requirements. The design was done considering phase-II & phase-III expansions in future. The facility has two sets of 20 KL, 2KL, 0.2KL & 0.02 KL fermenters & 2 Nos. of 7 KL Harvesters. The layout was planned as G+2 structure with service area on terrace. Modular & Aerocon panels were used on all the floors to ease dismantling and expansion of facility. The utility equipment's were located on terrace to reduce on pumping energy & associated piping inventory.

Client Name
Sanzyme Ltd.

Facility Type
Fermentation Facility

Project Location
Near Hyderabad, India

Project Duration
18 months (First Phase)
18 months (Second Phase)

Services Provided
  • Basic Engineering
  • Detail Engineering
  • Procurement Assistance
  • Site Supervision Support
  • Validation Support
Key Project Features
This facility produces various types of Probiotics. The facility is designed to meet the internal standards and international regulatory requirements. Two dedicated blocks one for probiotic and one for Lactic acid bacillus (LAB block) were planned in the plot. In addition there block specific areas for Raw Materials, Packaging Material, Finished products and Solvents. The support infrastructure such as Quality Control laboratory, Administration offices, Maintenance areas, ETP, Utility block, etc. are common for both the block.

The process involved for the LAB block includes fermentation, separation, drying (Spray drier) and powder processing. Powder processing area is designed as clean room and having control and monitoring of air as per ISO 8 requirement for HVAC system. Purified water as per USP grade was installed and was used for cleaning and rinsing of production equipment. Fermenters, three in numbers of 25KL each were installed in LAB block.

Second phase involved setting up four production unit connected to HUB and R&D.

Client Name
Kasiak Research (A Bharat Serums & Vaccines Ltd. Company)

Facility Type
Human & Animal Tissue Culture Laboratory

Project Location
Thane, India

Project Duration
7 months

Services Provided
  • Conceptual Planning
  • Basic Engineering
  • Detailed Engineering
  • Procurement Assistance
  • Qualification Support
Key Project Features
The facility was set up to process Human & Animal Cell Tissue Culture and produce some of the novel products. This was built in an existing structure and measures about 800 Sq. M.

The sections housed include Media Preparation room, Culture Handling rooms (Sterile), Wash area, Cryogenic Storage room, Wash & Decontamination zone, Autoclave zone and Change rooms. The key equipment installed include Bio-Safety Cabinets (Class 2), CO2 Incubators, Liquid Nitrogen Storage tanks, Cryogenic Storage Vessels, Centrifuges, Autoclaves, Dishwashers & Dryers, -20/ -80 deg. C Refrigerators.

The facility will be designed in accordance of containment requirement for managing infectious agents of BSL 2 category. The design objective is to protect the operators and others from exposure and also to protect the outside environment from potentially hazardous / infectious agents.

Client Name
Tex-Bioscience Pvt. Ltd.

Facility Type
Animal Feed Manufacturing Facility

Project Location
Chennai, India

Project Duration
12 Months

Services Provided
  • Basic Engineering
  • Detailed Engineering
  • Procurement Assistance
  • Project Management
Key Project Features
Tex-Bioscience Pvt. Ltd. is leading enzyme manufacturer and has manufacturing facilities for manufacturing textile and animal feed enzyme.

The facility was designed as multi-purpose facility to facilitate manufacturing of animal feed enzymes based on bacterial and fungal culture. The facility will be designed to meet HACCP guidelines applicable for Animal feed manufacturing.

The facility has two separate culture development and fermentation section each for Fungal and Bacterial fermentation. The production fermenter is 20 KL – 2 nos for each module.

The downstream processing involves Harvesting, filter press, centrifuge as one line and microfiltration and spray drying as other line. The final enzyme is blended with diluent and packed.

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