Services

  • JANSSEN CILAG PHARMACEUTICALS
    Pilot Plant
  • MERCK LTD.
    CH Innovation Lab
  • LUPIN LABORATORIES
    R&D Lab
  • NOVARTIS HEALTHCARE PVT. LTD.
    Lab and R&D Facility
  • NUTRICIA INTERNATIONAL LTD (DANONE GROUP)
    Pathogen Lab Facility
  • KASIAK RESEARCH
    Human & Animal Tissue Culture Laboratory

Client Name
Janssen Cilag Pharmaceuticals, (Johnson & Johnson)

Facility Type
Pilot Plant
(Hi-Potent Products)

Project Location
Mumbai, India

Project Duration
months (Phase wise Expansion)

Services Provided
  • Concept Design
  • Basic Engineering
  • Detail Engineering
  • Procurement Assistance
  • Site Audits
  • Construction Management
  • Commissioning & Start Up
  • Validation Support
Key Project Features
The Pilot Scale Manufacturing facility for Solids, Liquids & Ointments was set up at a project cost of INR 450 million and in a time span of 20 months. Services provided by spectrum include Basic Engineering, Detailed Engineering, Procurement Assistance, Commissioning & Validation Support and Construction Management.

The facility designed for handling PBOEL 3B compounds. It is proposed to be one of J&J's prime facilities for handling high potent formulations. Though the facility was a green field project, the constraint was that it was set up in an existing manufacturing site of Janssen Cilag in Mumbai. This site is located within a largely residential area of Mumbai, and there were lots of restrictions as far as usable ground space, height, environmental protection etc. were concerned.

The facility consists of the following main sections Ware House, Development lab, Pre Formulation Scale Manufacturing, Pilot Scale Manufacturing. Approximate built up area of the facility is 2000 Square meters. The facility is a Ground plus three-storied structure.

Client Name
Merck Ltd.

Facility Type
CH Innovation Lab

Project Location
Mumbai, India

Project Duration
6 Months

Services Provided
  • Concept Design
  • Basic Engineering
  • Detail Engineering
  • Procurement Assistance
  • Construction Management
  • Project Management
  • Commissioning
  • Validation Support
Key Project Features
This Project involved setting up of a R&D Lab in existing Laboratory of Pharmacy College by retrofitting them to accommodate spatial needs for the Laboratory. The Total area of allocated space is approx. 3000 Sqft and following key sections have been constructed in this Laboratory:
  • Formulation Development Lab
  • Analytical Lab
  • Stability Chamber Area
  • Raw Material and Finished Goods Store
  • Office and Meeting areas.

The project involved 2 major challenges in terms of execution:
  • Structural Strengthening: Since the Building Structure wasn’t designed for Heavy Equipment load which were to be placed in the Lab Areas. Extensive Structural Strengthening was undertaken.
  • Equipment Placement: The Lab was situated on 7th Floor of the Building. The Existing Lifts were small and of lesser Load carrying capacity, Also the Door Openings etc. were smaller hence a lot of thinking went into making sure the Equipment were placed at their designated locations smoothly.

Client Name
Lupin Laboratories

Facility Type
R&D Lab

Project Location
Aurangabad, India

Project Duration
20 Months

Services Provided
  • Concept Design
  • Basic Engineering
  • Detail Engineering
  • Procurement Assistance
  • Construction Management
  • Qualification & Validation Support
  • Cost Control
Key Project Features
The facility was set up in a time span of 20 months. Services provided by spectrum include Basic Engineering, Detailed Engineering, Procurement Assistance, Construction Management, Qualification & Validation Support and Cost Control. Approximate built up area of the facility is 2322 Square meters.

Salient Features:
  • State of the art R&D Facility
  • Formulation Development & Stability Studies
  • 60 Scientists
  • Existing injectable facility converted into laboratory
  • Unidirectional men & material movement is planned to avoid unwanted movements & to improve the production efficiency
  • Spacious Layout
  • Ergonomically designed lab furniture

Client Name
Novartis Healthcare Pvt. Ltd.

Facility Type
Lab and R&D Facility

Project Location
Thane, India

Project Duration
10 Months

Services Provided
  • Project Management
  • Basic Engineering
  • Detail Engineering
  • Procurement Assistance
  • Inspection & Expediting
  • Construction Management
  • Validation Support
Key Project Features
SPECTRUM designed and engineered a global research & development laboratory & pilot scale manufacturing facility for Novartis healthcare.
The main sections built in the center were:
  • Analytical Laboratory
  • Wet Chemistry Lab
  • Pilot Plant for OSD, Liquids & Semisolids
  • Stability Chambers' section
  • Offices for Chemists
  • Utility Area

The Project was done in existing building. Approximate area of he facility is 12,500 Square feet. Facility was planned to accommodate 25 Chemists. All utilities such as Lab Gases & Air compressors were located on Terrace. The major constraint in the project was that the Lab was located on 5th floor & all the utilities had to pass through the 6th floor to reach the Labs. This project was completed in record time of 10 Months and was appreciated as a state of the art facility & was qualified by Novartis, Switzerland's Quality Control Department

Client Name
Nutricia International Ltd. (DANONE Group)

Facility Type
Pathogen Lab Facility

Project Location
Lalru, Punjab, India

Project Duration
5 Months

Services Provided
  • Basic Engineering
  • Detail Engineering
  • Procurement Assistance
  • Project Management
  • Construction Management
  • Commissioning
  • Validation Support
Key Project Features
This lab is established for testing of Baby Nutrition Products being manufactured in the Facility. The project included Extension of Existing Plant, Furnishing and Installation of various utilities and testing equipment. The Facility has a Microbiology & Pathogen Lab along with allied spaces and Utilities. Executed on EPM basis. The Total area of allocated space is approx. 3000 Sq.ft and following key sections have been constructed in this Laboratory:
  • Pathogen Lab
  • Microbiology Lab
  • Preparation & Wash Area
  • Cold Room & Incubation Chambers
  • Material Store
  • Utility Areas

This was a Fast Track Project executed in less than 5 Months. Laboratory Designed and Executed as per DANONE Lab guidelines.

Client Name
Kasiak Research (A Bharat Serums & Vaccines Ltd. Company)

Facility Type
Human & Animal Tissue Culture Laboratory

Project Location
Thane, India

Project Duration
7 months

Services Provided
  • Conceptual Planning
  • Basic Engineering
  • Detailed Engineering
  • Procurement Assistance
  • Qualification Support
Key Project Features
The facility was set up to process Human & Animal Cell Tissue Culture and produce some of the novel products. This was built in an existing structure and measures about 800 Sq. M.

The sections housed include Media Preparation room, Culture Handling rooms (Sterile), Wash area, Cryogenic Storage room, Wash & Decontamination zone, Autoclave zone and Change rooms. The key equipment installed include Bio-Safety Cabinets (Class 2), CO2 Incubators, Liquid Nitrogen Storage tanks, Cryogenic Storage Vessels, Centrifuges, Autoclaves, Dishwashers & Dryers, -20/ -80 deg. C Refrigerators.

The facility will be designed in accordance of containment requirement for managing infectious agents of BSL 2 category. The design objective is to protect the operators and others from exposure and also to protect the outside environment from potentially hazardous / infectious agents.

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